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The suspect's name has not been released, but he has been identified as a 32-year-old male who is Australian of Afghan descent. He was arrested on the scene and was injured in the ramming. Police said 19 people were injured in the ramming, including the perpetrator and an off-duty police officer.

The suspect was released from the hospital into police custody.

When asked if there is a link to terrorism, Patton told 9News, "That's certainly what — one aspect we're exploring in respect to the motivation."

The suspect had a mental health appointment scheduled for Thursday before the ramming, but he missed the appointment, Patton said, adding that the suspect still needs to undergo a psychiatric assessment and be formally interviewed.

Police earlier said that the suspect, who was driving a white Suzuki SUV that was used in the ramming, has a history of drug abuse and mental health issues.

Authorities said the ramming, which occurred just after 4:30 p.m. local time, was a "deliberate act" but repeatedly said they do not yet know the motivation.

Of the 18 people taken to the hospital, 14 are still being treated, and three people are in critical condition.

Nine of the victims are from overseas, including three from South Korea, and one each from China, Italy, India, Venezuela, Ireland and New Zealand. No Americans were injured.

9News in Australia reported a 4-year-old girl was among those taken to the hospital with a serious head injury .

A second person detained Thursday near the site of the ramming was released, according to police. It was determined that he was not linked to the ramming, police said. However, the man was charged with possessing cannabis and a controlled weapon, police said. Police said earlier in the day three knives were found in his bag when detained.

All roads near the site of the ramming have been reopened to the public.

The area where the ramming occurred was filled with pedestrians and people doing holiday shopping.

"This is horrific. It's evil," Victoria Premier Daniel Andrews said. "We are not defined by these sorts of incidents."

Paul Calahane, a native of Ireland who said he has been in Melbourne for seven weeks, was returning home from work when the ramming unfolded behind him.

"I heard a bit of a bang behind me, even though I had my headphones in with a bit of audio," Calahane told ABC News. "I leaned forward, thinking it was a blast, then I saw people running. I saw people just scattered on the road ... There were people running, screaming, thinking it was a bomb."

Calahane said he turned to see across the street the white SUV, which had plowed into a light pole. He said a man was pulled out of the vehicle and arrested.

"Within a minute, there was about 40, 50 people on the scene," he said. "They were really pushing people back from the scene."

Then from noonto about 4 p.m. most people become more easily distracted once again. ()

If you didn’t get enough sleep last night or suffer from low-level chronic lack of sleep, you’ll have a hard time concentrating (or even staying awake!)

Insomnia has become a modern life epidemic.

Ourcircadian rhythms get confused by too little natural light and too much exposure tounnatural light in the evening. ()

The worst kind of light is the blue light emitted byTVs, computers, iPads, and smartphones.

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Water makes up 75% of the brain but most of us are chronically dehydrated. ()

Even mild dehydration results in shrinkage of brain tissue and temporary loss of cognitive function, including concentration and memory. ()

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It boosts blood flow to the brain to improve concentration, mood, andalertness.()

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Experiment with various sources of caffeine —coffee, tea, green tea, and yerba mate — to determine the best brew for you.

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Doing yoga can boost yourbrain power even more than doing conventional aerobic exercise.

Evenone session of yogasignificantly improves working memory and concentration. ()

The top yoga poses for better concentration include the plow, the camel, the cobra, the tree, and the corpse pose.

“Knocking on the Door of Life”is a qi gongexercisethat takes only three minutes.

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Marc A. Russo , Danielle M. Santarelli , Dean O’Rourke
Breathe 2017 13: 298-309; DOI: 10.1183/20734735.009817
Marc A. Russo
Hunter Pain Clinic, Broadmeadow, Australia
Danielle M. Santarelli
Hunter Pain Clinic, Broadmeadow, Australia
Dean O’Rourke
Hunter Pain Clinic, Broadmeadow, Australia ATUNE Health Centres, Warners Bay, Australia

Slow breathing practices have been adopted in the modern world across the globe due to their claimed health benefits. This has piqued the interest of researchers and clinicians who have initiated investigations into the physiological (and psychological) effects of slow breathing techniques and attempted to uncover the underlying mechanisms. The aim of this article is to provide a comprehensive overview of normal respiratory physiology and the documented physiological effects of slow breathing techniques according to research in healthy humans. The review focuses on the physiological implications to the respiratory, cardiovascular, cardiorespiratory and autonomic nervous systems, with particular focus on diaphragm activity, ventilation efficiency, haemodynamics, heart rate variability, cardiorespiratory coupling, respiratory sinus arrhythmia and sympathovagal balance. The review ends with a brief discussion of the potential clinical implications of slow breathing techniques. This is a topic that warrants further research, understanding and discussion.

Key points

Slow breathing practices have gained popularity in the western world due to their claimed health benefits, yet remain relatively untouched by the medical community.

Investigations into the physiological effects of slow breathing have uncovered significant effects on the respiratory, cardiovascular, cardiorespiratory and autonomic nervous systems.

Key findings include effects on respiratory muscle activity, ventilation efficiency, chemoreflex and baroreflex sensitivity, heart rate variability, blood flow dynamics, respiratory sinus arrhythmia, cardiorespiratory coupling, and sympathovagal balance.

There appears to be potential for use of controlled slow breathing techniques as a means of optimising physiological parameters that appear to be associated with health and longevity, and that may extend to disease states; however, there is a dire need for further research into the area.

Statistical analyses were coordinated across centres by the Lipoprotein Investigators Collaborative (LIC). TRIUMPH analyses were conducted with SAS version 9.2 (SAS Institute, Cary, NC, USA) and R version 2.7.2 (R Foundation for Statistical Computing, Vienna, Austria); IHCS analyses were conducted with SPSS version 15.0 (IBM, Chicago, IL, USA) and SAS version 9.3 (SAS Institute, Cary, NC, USA). Two-tailed P -values <0.05 were considered statistically significant.

The baseline sociodemographic and clinical characteristics of the TRIUMPH and IHCS cohorts are shown in Table 1 . Patients were middle-aged to elderly, and more than two-thirds were men. Approximately, two-thirds of patients were white in TRIUMPH, whereas IHCS was predominantly white. About one-third of TRIUMPH patients and 20% of IHCS patients had diabetes mellitus. A minority of patients in both cohorts had heart failure. A discharge statin prescription was given to 87.5% in TRIUMPH, and nearly half of IHCS patients were discharged on a statin. There were relatively low rates of use of other lipid-modifying agents such as ezetimibe, fibrates, or niacin.

Baseline lipid profile and HDL-C subclass information are presented in Table 2 . Mean baseline levels of total cholesterol, LDL-C, non-HDL-C, and triglycerides were below goal levels for high-risk patients as defined by NCEP ATP III. HDL-C levels were low (TRIUMPH: 40 ± 10.6 mg/dL; IHCS: 34.6 ± 10.1 mg/dL), and the ratio of total cholesterol to HDL-C was high (TRIUMPH: 4.1 ± 1.2; IHCS: 4.5 ± 2.0). HDL 3 -C accounted for more than three-fourths of HDL-C; the mean ratio of HDL 3 -C to HDL-C was 0.78 ± 0.05 in both cohorts. Apolipoprotein A1 was more tightly correlated with HDL 3 -C than HDL 2 -C ( Slimfit Buttondown Collar Selvedge Cottonchambray Shirt Officine Generale Outlet Recommend Really 4IB45YyBF
).

Table2

Baseline lipid parameters in TRIUMPH and IHCS

Mean (SD) or median (25th–75th percentile).

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Table2

Baseline lipid parameters in TRIUMPH and IHCS

Mean (SD) or median (25th–75th percentile).

View Large

Follow-up was 100% complete in both studies at 2 years. In addition, in IHCS, follow-up was 89 and 46% complete at 3 and 5 years, respectively. Mortality occurred in 226 (9.2%) TRIUMPH and 243 (10.1%) IHCS patients. A total of 208 (8.6%) IHCS patients were rehospitalized for MI. There were no significant differences in mortality rates between tertiles of HDL-C ( Supplementary material online, Table S2 ). Within subclasses, there were also no differences between HDL 2 -C tertiles. However, for the lowest tertile of HDL 3 -C compared with the middle and highest tertiles, approximately two-fold higher rates of events were observed for mortality in TRIUMPH and mortality or MI in IHCS. This finding emerged by 1 year in IHCS, and remained consistent over time.

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